GNRa-CSP12
| 【Numbering】BKMC116002 | 【CAS】CAS | ||
| 【Item No.】BKMC116002-2 | 【specification】 | ||
|
|||
Name: GNRa-CSP 12
Composition: Chitosan + 12-peptide + gold nanorods
Particle size: about 13,021 nm
Application: Treatment of acute myeloid leukemia
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] Low dose GNRa-CSP 12 can inhibit the growth of leukemic cells by damaging redox balance and inducing iron death. Mechanistic studies suggest that GNRa-CSP 12 is able to enable inactivity against endogenous Fe2 + -dependent m6A demethylase, resulting in m6A hypomethylation and post-transcriptional regulation of downstream genes. Combined treatment with GNRa-CSP 12 and tyrosine kinase inhibitors (TKIs) synergistically abolished the m6A-mediated TKI resistance phenotype.
Message
Composition: Chitosan + 12-peptide + gold nanorods
Particle size: about 13,021 nm
Application: Treatment of acute myeloid leukemia
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] Low dose GNRa-CSP 12 can inhibit the growth of leukemic cells by damaging redox balance and inducing iron death. Mechanistic studies suggest that GNRa-CSP 12 is able to enable inactivity against endogenous Fe2 + -dependent m6A demethylase, resulting in m6A hypomethylation and post-transcriptional regulation of downstream genes. Combined treatment with GNRa-CSP 12 and tyrosine kinase inhibitors (TKIs) synergistically abolished the m6A-mediated TKI resistance phenotype.
Title:Gold Nanorods Exhibit Intrinsic Therapeutic Activity via Controlling N6‑MethyladenosineBased Epitranscriptomics in Acute Myeloid Leukemia
Article link:https://www.163.com/dy/article/GOQ99DD70552LBIY.html
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
Message
|
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
Previous： the end...
Next： 仿生巨噬細胞膜載CRISPR/Cas9
