Nanozyme：Cu-HCF
| 【Numbering】BKMA104016 | 【CAS】CAS | ||
| 【Item No.】BKMA104016-2 | 【specification】 | ||
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Name: Cu-HCF
form:Cu, Fe
Particle size: 100 nm
Application: Promote the apoptosis of tumor cells
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [main advantages] 1. Cu-HCF nanoenzyme with a single copper active site has cascade enzyme activity (glutathione oxidase and peroxidase) in the tumor microenvironment. It was found that Cu-HCF single-site nanoenzymes (SSNEs) would first exert its glutathione oxidase activity to consume intracellular glutathione and convert single site CuII into CuI to further enhance its peroxidase activity, thus producing a large number of highly toxic hydroxyl radicals and promoting tumor cell apoptosis; the experimental results showed that SSNEs can effectively inhibit the growth of tumors in vivo, so this work provides a new and highly efficient platform for the anticancer application of cascade nanoenzymes.
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form:Cu, Fe
Particle size: 100 nm
Application: Promote the apoptosis of tumor cells
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [main advantages] 1. Cu-HCF nanoenzyme with a single copper active site has cascade enzyme activity (glutathione oxidase and peroxidase) in the tumor microenvironment. It was found that Cu-HCF single-site nanoenzymes (SSNEs) would first exert its glutathione oxidase activity to consume intracellular glutathione and convert single site CuII into CuI to further enhance its peroxidase activity, thus producing a large number of highly toxic hydroxyl radicals and promoting tumor cell apoptosis; the experimental results showed that SSNEs can effectively inhibit the growth of tumors in vivo, so this work provides a new and highly efficient platform for the anticancer application of cascade nanoenzymes.
Title:Self-Assembled Single-Site Nanozyme for Tumor-Specific Amplified Cascade Enzymatic Therapy
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688720143&ver=4635&signature=*3THxgsk-yV8yuNRV65R44SenoRyu9wnHRh-mFzM6rQUemWU1RSMx9PwsceiNsUs3xBuJ*gZVdewHEl3QyKpmVpAD1MEv2DEbz6XVRca6M5uJxDjxwoIoTXQ-4peQ9aa&new=1| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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